About InjectMate

InjectMate™ is a cannula introducer needle, designed to provide the safest, most efficient and easy delivery of cosmetic dermal fillers via a one-step injection process.

InjectMate is covered by U.S. Patent No. 10,028,768 (“Cannula and needle assembly,” inventor Gayle Misle, MD, granted July 24, 2018).

The blunt, hollow needle is inserted into the dermis and stays in place while a cannula is snaked through its opening. InjectMate™ provides 360 degree access from fewer injection sites, for easy and precise control to achieve smoother contouring with less bruising, swelling and pain.

Meet Dr. Gayle Misle, MD

InjectMate inventor, Founder & Medical Director at Reviv Medical Spa

Dr. Gayle Misle is dedicated to providing the safest cutting edge technology for skin rejuvenation and aesthetic improvement. She has participated in the Fellowship for Antiaging Medicine and is an accomplished member of the American Academy of Antiaging Medicine. She completed comprehensive training programs for aesthetic procedures, laser systems, skin tightening and wrinkle reduction, sclerotherapy, rich plasma skin rejuvenation and HCG hormone balance. Dr. Misle brings over a decade of experience as Chief of Anesthesia at San Leandro Hospital, as the Director of Anesthesiology at San Leandro Surgery Center, and as a pain management physician.

Dr. Misle is a graduate of the University of Nebraska College of Medicine. She was an Intern and resident in the Department of Anesthesiology at The University of Nebraska and the University of California at Davis. Her full background is on drgaylemisle.com, and her practice is Reviv Med Spa in Millbrae.

Why choose InjectMate?

May reduce tissue trauma

InjectMate is smaller and finer, causing less damage to surrounding tissue during insertion, leading to decreased pain and bruising for patients.

May lower risk of injuries

InjectMate shields the needle during insertion and remains within the cannula, reducing the likelihood of accidental needle stick injuries for both patients and healthcare providers.

May enhance patient comfort

The smaller size and flexibility of InjectMate result in a more comfortable experience for patients during injection procedures, minimizing tissue damage and nerve irritation.

May improve delivery and precision

InjectMate offers greater control and accuracy in delivering medication or fluids to specific locations within the body, ensuring precise placement for optimal treatment efficacy.

May decrease risk of extravasation

InjectMate cannulas are less likely to puncture through veins or arteries, reducing the risk of fluid leakage into surrounding tissues and preventing complications such as tissue damage and medication infiltration.

Versatility in sizing options

InjectMate comes in various sizes and lengths, making them suitable for a wide range of medical procedures and patient populations, providing versatility and flexibility in clinical practice. The evidence behind these points is collected on the benefits page.

Written and reviewed by Gayle Misle, MD, inventor · Last reviewed November 1, 2026